Table 1 Substitution rates and GC* in intronic regions
From: Both selective and neutral processes drive GC content evolution in the human genome
Substitution type | Fixed GC content | Fixed recombination rate | ||||
|---|---|---|---|---|---|---|
| Â | Low rec.a | High rec.a | p | Low GC | High GC | p |
A/T -> C/G | 0.00068 | 0.00091 | 1.9 × 10-6 | 0.00070 | 0.00075 | 5.6 × 10-3 |
A/T -> G/C | 0.00287 | 0.00366 | 1.9 × 10-6 | 0.00275 | 0.00324 | 1.9 × 10-6 |
A/T -> T/A | 0.00059 | 0.00065 | 6.3 × 10-5 | 0.00067 | 0.00056 | 5.7 × 10-6 |
C/G -> G/C | 0.00096 | 0.00114 | 1.9 × 10-6 | 0.00104 | 0.00101 | 1.2 × 10-2 |
C/G -> A/T | 0.00086 | 0.00099 | 1.9 × 10-5 | 0.00108 | 0.00087 | 1.9 × 10-6 |
C/G -> T/A | 0.00300 | 0.00336 | 1.9 × 10-6 | 0.00336 | 0.00300 | 1.9 × 10-6 |
CpG -> TpG | 0.02427 | 0.027713 | 1.9 × 10-6 | 0.03117 | 0.02352 | 1.9 × 10-6 |
GC* | 0.40750 | 0.43310 | 1.9 × 10-6 | 0.37349 | 0.42967 | 1.9 × 10-6 |
Number of sites (Mb) | 19.42 | 19.42 | - | 17.38 | 17.33 | - |