Mutant genotype | Relative fitness | Number | Epistasis | Hamming distance |
---|---|---|---|---|
WT | 1.000 ± 0.006 | 15 | ||
A16G | 0.918 ± 0.033 | 24 | 66 | |
C18A | 0.958 ± 0.042 | 12 | 0 | |
C23G | 0.962 ± 0.029 | 21 | 16 | |
A24U | 0.878 ± 0.057 | 21 | 0 | |
A37G | 0.861 ± 0.032 | 15 | 32 | |
G39U | 0.915 ± 0.033 | 30 | 0 | |
A46U | 0.910 ± 0.042 | 21 | 8 | |
A54G | 0.823 ± 0.058 | 21 | 49 | |
C57U | 0.808 ± 0.052 | 15 | 4 | |
G75U | 0.802 ± 0.061 | 18 | 47 | |
A83G | 0.927 ± 0.055 | 10 | 53 | |
A84G | 0.866 ± 0.037 | 35 | 10 | |
C91U | 0.913 ± 0.033 | 32 | 0 | |
C100G | 0 | 30 | 48 | |
C106U | 0.896 ± 0.051 | 24 | 37 | |
C127U | 0 | 30 | 53 | |
U131C | 0.997 ± 0.023 | 15 | 0 | |
A135G | 0.971 ± 0.033 | 27 | 7 | |
G138U | 0.985 ± 0.023 | 24 | 2 | |
G142A | 0.873 ± 0.038 | 27 | 32 | |
A16G/C23G | 0.999 ± 0.024 | 24 | 0.117 ± 0.089 | 40 |
A16G/C100G | 0.902 ± 0.042 | 27 | 0.903 ± 0.048 | 33 |
A16G/C127U | 0 | 30 | 0 | 53 |
A16G/A135G | 1.012 ± 0.020 | 21 | 0.120 ± 0.089 | 7 |
C18A/C100G | 0 | 30 | 0 | 48 |
C23G/A24U | 0.932 ± 0.034 | 21 | 0.088 ± 0.120 | 10 |
C23G/A54G | 1.040 ± 0.005 | 3 | 0.250 ± 0.091 | 57 |
C23G/142A | 0 | 30 | −0.839 ± 0.062 | 40 |
A24U/C106U | 1.031 ± 0.056 | 21 | 0.244 ± 0.159 | 37 |
A37G/C106U | 0.899 ± 0.024 | 21 | 0.127 ± 0.102 | 18 |
A37G/A135G | 0.956 ± 0.004 | 30 | 0.120 ± 0.070 | 7 |
G39U/C91U | 0.901 ± 0.032 | 27 | 0.066 ± 0.098 | 0 |
A46U/A135G | 0.900 ± 0.013 | 32 | 0.017 ± 0.090 | 15 |
C57U/G75U | 0.906 ± 0.039 | 30 | 0.259 ± 0.135 | 8 |
C57U/A83G | 0.823 ± 0.052 | 9 | 0.074 ± 0.150 | 45 |
C57U/C127U | 0.949 ± 0.037 | 27 | 0.949 ± 0.043 | 35 |
A83G/C100G | 1.019 ± 0.019 | 18 | 1.019 ± 0.026 | 53 |
A84G/G142A | 0.999 ± 0.014 | 24 | 0.244 ± 0.086 | 32 |
C91U/U131C | 1.016 ± 0.015 | 30 | 0.106 ± 0.075 | 0 |
C91U/A135G | 0.833 ± 0.007 | 3 | −0.053 ± 0.074 | 7 |
C100G/C106U | 0.751 ± 0.035 | 11 | 0.751 ± 0.040 | 48 |
C100G/G138U | 0.635 ± 0.002 | 3 | 0.635 ± 0.006 | 33 |
C127U/A135G | 0.816 ± 0.077 | 6 | 0.817 ± 0.082 | 7 |
U131C/G142A | 0.705 ± 0.048 | 6 | −0.166 ± 0.111 | 20 |
A135G/G138U | 0 | 10 | −0.957 ± 0.055 | 9 |