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Table 1 Properties and origins of NIPs.

From: Some novel intron positions in conserved Drosophila genes are caused by intron sliding or tandem duplication

nt FBgn apomorphic introns Properties typical for intron sliding Properties typical for tandem duplication
    No intermediate, intron-less state in the tree Multiple-of-three NIP distances that made a stepwise intron shift possible Cryptic splice sites, occurring in NIP distance and supported by amino acid conservation One-sided shifts or GYRGYR/NAGNAGs in some species Significant sequence similarity between introns of both positions Proto-splice site (AG/GY) plesiomorphic introns not identifiable
probably migrated intron positions
3 3607 118-1 x x   x    
3 32261 55-0 x x   x    
3 37757 616-1 x x   x x   
6 19809 255-0 x x   x    
6 35879 105-1 x x x   x   
9 32821 1200-0 x x x     
9 34221   x x    x   x
12 33734 419-0, 423-0 x x   x    
15 1124 124-0 x x x     
introns probably gained by tandem (exon) duplication
10 30661        x  
21 29747   x x     2x x
30 38300   x x     2x x
30 50101 251-0 x x     x  
31 2526        x x
NIPs of unknown origin
2 31216 1927-1, 1928-0 x       x
2 36142 456-0, 456-2 x   x     
3 15572 4-2 x x      
3 32087 19-1 x x      
3 32504    x      x
3 52081   x x      x
5 46689 16-2 x   x     
6 31395   x x      x
9 38302 65-2 x x      
14 35965 44-0 x       
16 33686 53-2, 59-0 x       x
21 30055   x x      x
22 32517 221-0 x       
23 33247 45-2 x       
24 34793 29-0 x x      
27 1185    x      x
28 31773 164-1 x       
31 25 27 21 5 5 3 7 11
  1. "nt" means NIP distance in nucleotides. Note that each of the 9 NIPs resulting supposedly from intron sliding shows at least three of the expected properties and/or a significant sequence similarity between introns of both positions (Materials and Methods). Introns gained by tandem duplication show a proto-splice site. In addition, a plesiomorphic intron is not identifiable because both introns probably have been gained by the same duplication.