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Table 3 Conservation of five putative calcium coordinating residues in C2 domains.

From: Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins

 

Dysferlin

Paralogs

Orthologs

C2A

No

N/A

N/A

C2B

No

N/A

N/A

C2C

Yes

No

No

C2D

Yes

No

Yes (1,2)

C2E

Yes

Yes

Yes (1)

C2F

Yes

Yes

Yes(1)

  1. Key: Yes indicates that all five aspartates are conserved; No indicates all five could not be identified; N/A indicates these domains were not tested for aspartates as the corresponding dysferlin C2 domains have not conserved the five aspartates; 1 indicates no conservation in Cele; 2 indicates no conservation in Dmel. Residues considered as having potential for calcium coordination include aspartic and glutamic acid.
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BMC Ecology and Evolution

ISSN: 2730-7182

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