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Table 1 Comparison of ABC transporters in Tetrahymena thermophila and other eukaryotes

From: Genome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene family

Family Structure Tt Pt Bb Py Dd At Sc Hs
ABCA (TMD-NBD)2 29a 20 0 0 7 0 0 13
  TMD-NBD 4 4 0 0 5 17b 0 0
ABCB (TMD-NBD)2 13 7 0 1 2 22 1 4
  TMD-NBD 13 7 4 6 7 5 3 7
ABCC (TMD-NBD)2 60 46c 4 1 14 15 7 12
ABCD (TMD-NBD)2 0 0 0 0 0 1 0 0
  TMD-NBD 2 4 0 0 3 1 2 4
ABCE NBD-NBD 1 2 1 1 1 2 1 1
ABCF NBD-NBD 2 2 1 1 4 5 5 3
ABCG (TMD-NBD)2 3 0 0 0 15 13 10 0
  TMD-NBD 36 17 0 1 6 29 1d 5
Othere NBD 2 3 0 3 4 15 2 2
Total - 165 112 10 14 68 125 32 50
Number of Genes - 24725 39642 3671 5878 12500 25498 5538 22287
Percent - 0.667% 0.283% 0.272% 0.238% 0.544% 0.490% 0.577% 0.224%
  1. Tt = Tetrahymena thermophila, Pt = Paramecium tetraurelia, Bb = Babesia bovis (has the minimum predicted gene number in sequenced apicomplexans), Py = Plasmodium yoelii yoelii (has the maximum predicted gene number in sequenced apicomplexans), Dd = Dictyostelium discoideum, At = Arabidopsis thaliana, Sc = Saccharomyces cerevisiae, Hm = Homo sapiens
  2. a one incorrectly predicted gene was identified
  3. b includes a gene annotated as (TMD-NBD)2 in a previous report, but revised as TMD-NBD in the current version of the annotation
  4. c includes 5 genes with a structure TMD-NBD and 2 genes with a structure NBD
  5. d this gene has three TMDs and one NBD
  6. e includes the ABCH family of gene