Figure 2

Dynamics of the basic model (consisting of wild-type cells, cells with resistance on the chromosome and plasmid-carried resistance) in response to different treatment regimes. "F" denotes wild-type cells, "P" denotes cells infected with a plasmid carrying resistance, "C" denotes cells with resistance on the chromosome and "CP" stands for cells with resistance on the chromosome that also carry a resistance plasmid. Parameters used are r = 1, a = 1, β = 0.006, s = 0.001, c_c = 0.002, c_p = 0.002, x = 0.002, m = 0.1 and l = 0.005. The dosage is 50 in both panels, while the treatment interval is τ = 5 time units in the top panel and τ = 50 time units in the bottom panel. Time in our model is scaled, and is thus measured in arbitrary units (AU).