Figure 5

Gene structures of alternatively spliced coronins. The cartoons outline the gene structures of the alternatively spliced coronin-1 gene from Caenorhabditis elegans, CeCoro1, and the coronin-1D gene from Homo sapiens, HsCoro1D. The alternatively spliced CeCoro1 gene contains a differentially included exon8, which has an additional alternative 3'-splice site, leading to three transcripts. The other two described splice sites, an alternative 3'-splice site of exon7 and an alternative 5'-splice site of exon8 [35], are most probably artificial. The HsCoro1D gene contains a cluster of two mutually exclusive spliced exons, exon5a and exon5b, and an alternative 5'-splice site of exon10. Dark grey bars and light grey bars mark exons and introns, respectively, and alternative exons and splice sites are coloured.