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Figure 5 | BMC Evolutionary Biology

Figure 5

From: The effects of linkage on comparative estimators of selection

Figure 5

Diagnostic for hitch-hiking. Circles and bars indicate median and interquartile ranges from all combinations of recurrent sweeps with τ=103,104, s b =10−3,10−2, u=10−5,10−6and β=0.25,0.5,1,2. Parameter combinations which give a median â B <0 are denoted with an open circle whereas simulation conditions which result in â B >0 are shown with closed circles. The x-axis is the relative excess of non-synonymous substitutions due to linked positive selection, calculated as ( k ̄ k ̄ )/ k ̄ averaged across all time points after 40000 generations, where k ̄ is the mean number of non-synonymous substitutions at non-beneficial sites averaged across 500 simulations with no positive selection and the prime indicates the corresponding values in a simulation with both positive and negative selection.

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