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Table 6 Eukaryotic clusters

From: Coiled-coil protein composition of 22 proteomes – differences and common themes in subcellular infrastructure and traffic control

Cluster size (# of sequences) Max. edge (P-score) protein family putative function/site of action organisms represented
94 5.4E-10 Myosin heavy chain actin motor protein (muscle, cytoskeleton) A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p.
27 1.5E-36 Kinesin heavy chain (KCBP, KIFC) MT motor protein (cytoskeleton) A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p.
21 1.1E-35 Kinesin heavy chain (Cmet/Cana, MKRPs, NACK/HINKEL) MT motor protein (cytoskeleton) A.t., D.m., H.s., M.m., O.s., S.p.
17 1.2E-7 Structural maintenance of chromosomes 5–6/RAD18 DNA repair (chromatin) A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p.
12 5.0E-7 Kinases (GIN4, MET) signal transduction A.t., D.m., H.s., O.s., S.c.
11 <E-40 RAD50 (eukaryotic) DNA repair A.t., C.e., D.m., H.s., M.m., O.s., S.c., S.p.
11 1.2E-7 Retinoblastoma-associated protein, RING finger protein 20 E3 Ubi. ligase for H2B histone modification (nuclear)? A.t., C.e., D.m., H.s., M.m., O.s., S.c, S.p.
  1. Numbers include "bridge" sequences qualifying for more than one cluster. Only clusters represented by at least 10 sequences are listed. MKRPs, mitochondrial kinesin-related proteins [122]; NACK/HINKEL, NPK1-activating kinesin [123]; MET, [124]. For species name abbreviations, see Table 1.