Cluster size (# of sequences) | Max. edge (P-score) | protein family | putative function/site of action | organism |
---|---|---|---|---|
57 | 3.3E-7 | Myosin heavy chain XVIII | non-muscle and smooth muscle myosins | C.e., D.m., H.s., M.m., S.p. |
50 | 6.5E-8 | Myosin heavy chain type 2 | actin motor protein (cytoskeleton) | C.e., D.m., H.s., M.m., S.c., S.p. |
27 | <E-40 | Dynein heavy chain | MT motor (cytoskeleton, flagella) | C.e., D.m., H.s., M.m., S.c. |
17 | 3.1E-9 | Intersectins, Eps15 | endocytosis | C.e., D.m., H.s., M.m., S.c., S.p. |
16 | 9.5E-7 | Png-1, IF-2, Neurofilament triplet L, Troponin T | D.m., H.s., M.m., O.s., S.c. | |
14 | <E-40 | Restin, Dynactin, CLIP proteins | linking endocytic vesicles to MTs (IF cytoskeleton), dynein activator (MTs in neurons), MT/IF associated (cytoskeleton) | C.e., D.m., H.s., M.m., S.c., S.p. |
14 | 1.6E-15 | Myosin heavy chain V | unusual myosin | C.e., D.m., H.s., M.m., S.c. |
14 | <E-40 | DRFs | binds Rho-GTP and profilin, promotes actin polymerization (membrane cytoskeleton) | D.m., H.s., M.m., S.c. |