Tracing the origin of functional and conserved domains in the human proteome: implications for protein evolution at the modular level

Table 1 Comparison of the performance of HHpred against Hmmpfam in detecting remote homologs

	HHpred method	Hmmpfam method
Pfam-A hits for sequences	74%	64%
Residues covered by Pfam-A hits	54%	34%
Unique Pfam-A families found	3853	3192

ISSN: 2730-7182