Figure 1
From: Conserved and species-specific alternative splicing in mammalian genomes
Conservation and inclusion level of cassette exons. Horizontal axis: inclusion level (fraction of ESTs covering an alternative region and containing the exon, see the text for detailed definitions). Top plot: Red diamonds and blue squares – percent of human exons in each bin that are conserved in the mouse and dog genomes, respectively. Crescent piecharts below: sizes of circle segments are proportional to the total number of human exons in the given bin that are conserved in both mouse and dog (grey), conserved only in mouse or dog (red and blue respectively), or human-specific (green). The percentages of these types of exons are given in the table in the middle. The leftmost bin contains exons with inclusion frequency less than 1%; the rightmost bin contains exons with skipping frequency less than 1%. Both represent possible splicing errors, see the text for details. Top: frame-preserving exons. Bottom: frame-shifting exons