Molecular evolution of bovine Toll-like receptor 2 suggests substitutions of functional relevance

Table 1 Significantly positive selected sites

Position	AA	P	ω	Position	AA	P	ω
3	R	0.98591	1.84	279	I	0.99157	1.847
7	T	0.97386	1.824	296	R	0.99915	1.857
8	A	0.98487	1.838	297	A	0.99833	1.856
20	G	0.9561	1.801	298	L	0.99039	1.846
21	A	0.99537	1.852	299	S	1	1.858
23	D	0.99588	1.853	300	L	1	1.858
32	P	0.9598	1.806	302	R	0.99562	1.852
33	T	0.96925	1.818	304	R	0.99646	1.854
39	H	0.99755	1.855	305	H	0.99983	1.858
52	A	0.99338	1.85	306	L	0.99544	1.852
74	R	0.96928	1.818	326	H	0.9823	1.835
82	R	0.99748	1.855	336	G	0.96614	1.814
84	G	0.99999	1.858	337	R	0.97197	1.821
98	H	0.98764	1.842	373	S	0.99991	1.858
111	R	0.99686	1.854	376	T	0.99962	1.858
125	V	0.99792	1.855	384	D	0.99406	1.85
135	L	0.99946	1.857	400	K	0.99999	1.858
149	P	0.98322	1.836	408	L	0.99983	1.858
159	S	0.99998	1.858	440	Q	0.99993	1.858
166	H	0.98063	1.833	453	Q	1	1.858
167	E	0.99467	1.851	471	S	0.99083	1.846
182	S	0.99939	1.857	502	S	0.99786	1.855
184	Q	0.99998	1.858	508	R	0.98935	1.844
188	I	0.99979	1.858	510	I	0.99123	1.847
221	V	1	1.858	512	N	0.96372	1.811
235	H	0.99283	1.849	523	Q	0.9997	1.858
242	A	0.99239	1.848	524	Q	0.99985	1.858
244	I	0.99197	1.848	553	R	0.99999	1.858
245	S	0.99752	1.855	556	V	0.98053	1.833
247	M	0.99991	1.858	560	D	0.99864	1.856
250	S	0.98942	1.844	561	D	0.99969	1.858
260	Q	0.99472	1.851	636	R	0.99989	1.858
267	V	0.99995	1.858	650	R	0.96011	1.806
274	N	0.95099	1.794	766	V	0.9999	1.858
275	Y	0.98963	1.845

Position: position in the protein sequence, AA: amino acid at this position in cattle, p: probability of class assignment as positively selected site, ω: dN/dS ratio

ISSN: 2730-7182