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Table 3 Pooled progeny of USP4- and USP15-null mouse crosses

From: Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11

    USP 15   
   wt het null Total
  wt 23 29 17 69
USP4 het 21 35 11 67
  null 8 22 0 30
  Total 52 86 28 166
  1. Mice heterozygous for inactivating mutations of both USP4 and USP15 were mated, and progeny genotyped by polymerase chain reaction analysis. The number of progeny of each genotype is indicated, where wt represents homozygous wild-type, het represents heterozygous, and null represents homozygous null mice. The absence of progeny null for both USP4 and USP15 is statistically significant (p = 0.000022)