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Table 3 Non-synonymous (dN) and synonymous (dS) substitutions (± standard deviation) for C. perspicillata, D. rotundus and M. molossus

From: Spatial pattern of genetic diversity and selection in the MHC class II DRB of three Neotropical bat species

Species

Region

N

dN ± SD

dS ± SD

dN/dS

Z-test

p-value

C. perspicillata

 

ABS

25

0.405 ± 0.131

0.082 ± 0.064

4.939

5.119

<10-5

 

Non-ABS

64

0.121 ± 0.047

0.043 ± 0.029

2.792

3.283

0.0013

 

All

89

0.187 ± 0.053

0.0528 ± 0.026

3.548

5.619

<10-5

D. rotundus

 

ABS

25

0.314 ± 0.116

0.077 ± 0.055

4.081

3.811

0.0002

 

Non-ABS

64

0.049 ± 0.035

0.045 ± 0.032

1.075

0.156

0.8764

 

All

89

0.114 ± 0.470

0.054 ± 0.032

2.119

2.713

0.0077

M. molossus

 

ABS

21

0.323 ± 0.103

0.068 ± 0.058

4.753

4.080

0.0001

 

Non-ABS

60

0.060 ± 0.021

0.056 ± 0.031

1.078

0.186

0.8528

 

All

81

0.120 ± 0.028

0.058 ± 0.030

2.049

2.599

0.0105

  1. Putative ABS and non-ABS were identified assuming functional homology to the human ABS of the HLA-DR1 molecule Brown et al. [65]. N is the number of codons in each sequence region. Z-test values and p-values are shown