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Table 3 Site-specific comparisons for 9 CYP loci in 25 avian species

From: Evolution of CYP2J19, a gene involved in colour vision and red coloration in birds: positive selection in the face of conservation and pleiotropy

  LRT Statistic p-value Corrected p-value M2a M8
CYP gene M1a- M2a M7-M8 M1a- M2a M7-M8 M1a- M2a M7-M8 Freq of sites with ω > 1 ω > 1 Positively selected sites under BEB P > 95% (bold: P > 99%) Freq of sites with ω > 1 ω > 1 Positively selected sites under BEB P > 95%(bold: P > 99%)
CYP2J19 4.577 49.376 0.101 0.000   0.000* 0.018 1.944   0.083 1.387 8, 37, 233, 455
CYP2J40 76.397 84.911 0.000 0.000 0.000* 0.000* 0.038 2.974 56, 59, 60, 61, 80, 247, 250, 393 0.056 2.246 56, 59, 60, 61, 80, 247, 250, 393
CYP19A1 0.000 3.579 1.000 0.167    0.020 1.000   0.011 1.031  
CYP7A1 0.000 9.871 1.000 0.007   0.065 0.030 1.000   0.062 1.331  
CYP8B1 11.835 46.986 0.003 0.000 0.024* 0.000* 0.028 2.170   0.101 1.506 104
CYP4V2 57.130 64.122 0.000 0.000 0.000* 0.000* 0.031 3.160 31, 67, 69, 75, 272 0.043 2.603 31, 57, 67, 69, 75, 145, 272
CYP3A9 57.980 86.997 0.000 0.000 0.000* 0.000* 0.059 2.504 88, 95, 135, 149, 203, 279, 466 0.081 2.095 4, 87, 88, 95, 135, 149, 203, 223, 279, 309, 466, 470
CYP7B1 8.154 25.295 0.017 0.000 0.153 0.000* 0.017 2.468   0.023 2.220 89, 348, 437, 458
CYP20A1 0.000 5.957 1.000 0.051    0.047 1.000   0.014 1.833  
  1. Underlined sites fall within predicted functional domains for CYP2 proteins annotated in Almeida et al. 2016 [22]
  2. *Significant result at p < 0.05 after p-value correction for multiple testing