Fig. 3
a) The proportion of the different selected resistance mechanisms and b) their sensitivity to initial parameters for a low, an intermediate and a high cost of resistance (bmin = 0.3, bmin = 0.2 and bmin = 0.1 respectively) for the key organ and the auxiliary organ considered in isolation and considered in interaction through metastasis. In b) the Partial Rank Correlation Coefficient (PRCC) are calculated between the seven input parameters and the selected resistance mechanisms in the key organ (λa) and the auxiliary organ (λb). The significant correlations are in bold (t-test, p < 0.01). The main selective forces are in red