Fig. 5

Reconciled gene tree of Hint1/Hint2. As mentioned in the main text, only unambiguous parts of the tree are shown. Red arrows indicate duplication events; species names of duplicates are shown in bold. Next to the tree, a schematic view of the recurrent pattern is shown. Shaded areas indicate the predicted fate (Hint1 and Hint2 after the human genes). The sequences are shown as horizontal bars, aligned at position 1 (Met) of human Hint1. Residues that appear N-terminal to this are represented by a thick blue bar. On the right, the subcellular localization as predicted by TargetP is shown (Mito: mitochondrion, Chlo: chloroplast, Secr: secretory, Cyto: cytoplasm)