Fig. 6

Schematic representation of eleven putatively conserved proteins identified in OM of the red coral and the scleractinian coral biominerals and their percentage of identity and similarity. Names, Proteome_ID and sequence description of the 11 C. rubrum proteins are indicated (left). Their presence in the different biomineral fractions is represented with circle as in Fig. 2b, and protein domains are described in the box. The 11 putative homologs were present in the published skeletome of 3 scleractinian species [16, 18, 21] and the OM of C. rubrum biominerals of our study (see Additional file 3 sheet#2). Percentage of identity and similarity between proteins of C. rubrum and proteins identified in the skeletome of the 3 other scleractinian species (Additional file 11) were calculated using https://www.bioinformatics.org/sms2/ident_sim.html and are indicated in the table (right; N: no putative homolog). For each scleractinian protein, GenBank accession number is indicated and published sequence name is given in brackets. Scale bars = 100 amino acids. AMOP adhesion-associated domain present in MUC4 and other proteins, Cadh cadherin repeats, Cadh_C cadherin_C, CAP cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 protein, CA carbonic anhydrase, EGF epidermal growth factor, HH_Nterm hedgehog, IG-like immunoglobulin-like, IGc2 immunoglobulin C-2 type, LamG laminin G, LCD low complexity domain, LDLa low-density lipoprotein receptor domain class A, LY low-density lipoprotein receptor YWTD domain, NIDO extracellular domain of unknown function in nidogen, SH2 Src homology 2, SP signal peptide, TM transmembrane, Tryp_SPc trypsin-like serine protease, TSP1 thrombospondin-1, vWA von Willebrand type A, vWD von Willebrand type D