Fig. 1From: Region-specific expression of young small-scale duplications in the human central nervous systemSpecific expression of protein coding genes across human CNS regions. a Density plot of original Tau scores (blue line) calculated from the expression values of 16,427 protein coding genes, and permutated Tau scores (purple line) calculated from 1000 × 16,427 permutations. The region-specificity threshold of 0.525 (red dotted line) is defined, from permutated scores using the Benjamini–Hochberg corrected p-value of 0.01. b Unsupervised hierarchical clustering of region-specific genes expressed across CNS territories. The heatmap illustrates the mean gene expression calculated over samples of the cohort for each CNS regionBack to article page