Fig. 5
From: “Patchiness” in mechanical stiffness across a tumor as an early-stage marker for malignancy
Change in mean stiffness of the cells against c value (ratio of local to global diversity). Window size of 4 × 4 × 4 cell lengths (40 μm x 40 μm x 40 μm) used to calculate the patchiness index using Eq. 5. Each open red circle represents the change in mean cell stiffness over 20 cell death and division cycles for a single simulation, plotted against the patchiness index of the starting initial tissue configuration for that simulation run. The error bars are standard errors of the mean. Stars above the bar plots indicate p values < 0.05 for a single population ttest